⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179699 | 1.00 | — | — | |
| SCHEMBL15849491 | 1.00 | — | — | |
| SCHEMBL13369649 | 0.87 | — | — | |
| SCHEMBL2313043 | 0.87 | — | — | |
| SCHEMBL16689075 | 0.86 | — | — | |
| SCHEMBL19015223 | 0.85 | — | — | |
| SCHEMBL16016150 | 0.83 | ALDH1A1 (0.35) | — | |
| SCHEMBL1560004 | 0.79 | ALDH1A1 (0.44) | — | |
| SCHEMBL15572079 | 0.79 | — | — | |
| SCHEMBL3099816 | 0.76 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082357-B | Hexahydrofuro [2,3-b ] furan nicotine compound, and preparation method and application thereof | 南京工业大学 | 2025-05-13 | — | — | CN | claimed |
| CN-116103348-A | Process for preparing hexahydrofurofuranol derivative, intermediate and process for preparing the same | 江苏瑞科医药科技有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116082357-A | Hexahydrofuro [2,3-b ] furan nicotine compound, and preparation method and application thereof | 南京工业大学 | 2023-05-09 | — | — | CN | claimed |
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | claimed |
| EP-0619821-A1 | HEXAHYDROFURO(2,3-b)FURANS AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-19 | — | — | EP | claimed |
| WO-1993008194-A1 | HEXAHYDROFURO(2,3-b)FURANS AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-04-29 | — | — | WO | claimed |
| US-12465590-B2 | Oxalamido-substituted tricyclic inhibitors of hepatitis b virus | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2025-11-11 | — | — | US | disclosed |
| CN-116082357-B | Hexahydrofuro [2,3-b ] furan nicotine compound, and preparation method and application thereof | 南京工业大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-116082357-B | Hexahydrofuro [2,3-b ] furan nicotine compound, and preparation method and application thereof | 南京工业大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-116082357-B | Hexahydrofuro [2,3-b ] furan nicotine compound, and preparation method and application thereof | 南京工业大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119409710-A | Oxamide substituted hepatitis b virus tricyclic inhibitors | 圣拉斐尔医院有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-114555608-B | Oxamide substituted hepatitis b virus tricyclic inhibitors | 圣拉斐尔医院有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-113620944-B | Novel RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2002022577-A2 | HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS | NOVARTIS AG (CH) | 2002-03-21 | — | — | WO | disclosed |
| US-5409937-A | Hexahydrofuro(2,3-b)furans as PAF antagonists | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-04-25 | — | — | US | disclosed |
| US-5409937-A | Hexahydrofuro(2,3-b)furans as PAF antagonists | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-04-25 | — | — | US | disclosed |
| EP-0619821-A1 | HEXAHYDROFURO(2,3-b)FURANS AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993008194-A1 | HEXAHYDROFURO(2,3-b)FURANS AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0154254-A1 | Bicyclic amide ketal derivatives | THE DOW CHEMICAL COMPANY (US) | 1985-09-11 | — | — | EP | disclosed |
| US-4501679-A | WATER OR ACID SCAVENGERS | THE DOW CHEMICAL COMPANY (US) | 1985-02-26 | — | — | US | disclosed |