Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253362 | 0.86 | — | — | |
| SCHEMBL2243600 | 0.84 | — | — | |
| SCHEMBL2247079 | 0.84 | — | — | |
| SCHEMBL12355683 | 0.83 | — | — | |
| SCHEMBL12355685 | 0.83 | — | — | |
| SCHEMBL12355627 | 0.81 | DRD2 (0.33) | DRD2DRD4DRD3 | |
| SCHEMBL12355692 | 0.78 | — | — | |
| SCHEMBL2246339 | 0.78 | DRD2 (0.35) | DRD2 | |
| SCHEMBL12355690 | 0.77 | — | — | |
| SCHEMBL2247015 | 0.76 | CA12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989451-B2 | Tricyclic 1,2,4-triazine oxides and compositions for therapeutic use in cancer treatments | AUCKLAND UNISERVICES LIMITED (NZ) | 2011-08-02 | — | — | US | disclosed |