Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.46 |
| ▸ | GABRP | O00591 | 6/20 | 0.46 |
| ▸ | GABRD | O14764 | 6/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.46 |
| ▸ | GABRE | P78334 | 6/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912573 | 0.88 | POLB (0.51) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL10003611 | 0.87 | CYP1A2 (0.53) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL127058 | 0.86 | POLB (0.49) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL1645417 | 0.84 | CYP1A2 (0.50) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL14288423 | 0.83 | POLB (0.49) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL31172634 | 0.83 | CYP4F2 (0.50) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL480097 | 0.83 | POLB (0.53) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| Alcohol SCHEMBL11011386 | 0.83 | POLB (0.49) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL3588853 | 0.82 | POLB (0.49) | POLBCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL11633585 | 0.82 | CA12 (0.50) | POLBCYP1A2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190279-A1 | SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190254-A1 | CEPHALOSPORIN HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| EP-2341053-A1 | CEPHALOSPORIN HAVING CATECHOL GROUP | Shionogi & Co., Ltd. (JP) | 2011-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190254-A1 | CEPHALOSPORIN HAVING CATECHOL GROUP | NRDC, LUC7L2, NR0B1 | POLB 1717/4885CYP1A2 1461/4885GABRA1 2133/4885 |
| US-20110190279-A1 | SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY | BACE1, BACE2, APP | POLB 1383/4885CYP1A2 2552/4885GABRA1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.