SCHEMBL12361

SCHEMBL12361

Cc1ccc2cccnc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
CYP1A2 P05177 2/20 0.59
HTT P42858 2/20 0.59
MEN1 O00255 1/20 0.59
CASP1 P29466 1/20 0.59
CASP7 P55210 1/20 0.59
KMT2A Q03164 1/20 0.59
CYP2C19 P33261 1/20 0.59
NR4A2 P43354 1/20 0.59
PDGFRB P09619 1/20 0.50
PDGFRA P16234 1/20 0.50
CCR1 P32246 2/20 0.48
CCR5 P51681 2/20 0.48
CCR8 P51685 2/20 0.48
NQO2 P16083 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP2A6 P11509 1/20 0.48
P2RY14 Q15391 1/20 0.48
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518639 1.00 ALDH1A1 (1.00) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL30489850 1.00 ALDH1A1 (1.00) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL6047936 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL29097106 0.89 ALDH1A1 (0.79) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL3773100 0.85 ALDH1A1 (0.72) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL24621720 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL24621869 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL12386953 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HTTMEN1CASP1
Quinoline SCHEMBL28182317 0.84 ALDH1A1 (0.71) ALDH1A1CYP1A2HTTMEN1CASP1
SCHEMBL130884 0.83 ALDH1A1 (1.00) ALDH1A1CYP1A2HTTMEN1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2696 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003449-B Synthesis method of tetrahydroquinoline compound with C-B bond 广东以色列理工学院 2025-02-28 CN claimed
CN-119340463-A Long-life wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN claimed
CN-119340464-A Novel wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN claimed
CN-118702623-A Purification method of 7-methylquinoline 江苏宏邦化工科技有限公司 2024-09-27 CN claimed
CN-118667065-A Self-supporting polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2024-09-20 CN claimed
CN-117160451-A Platinum-tin bimetallic catalyst for quinoline compound reduction methylation and preparation method and application thereof 浙江大学衢州研究院 2023-12-05 CN claimed
CN-113176253-B Occult blood indicator for animal excrement and application thereof 上海麦可信生物科技有限公司 2023-05-23 CN claimed
CN-114891212-A Preparation method of high-temperature-resistant polyimide film 苏州聚萃材料科技有限公司 2022-08-12 CN claimed
CN-113176253-A Animal excrement occult blood indicator and application thereof 上海麦可信生物科技有限公司 2021-07-27 CN claimed
CN-111039723-A Water-soluble fertilizer containing amino acid and calcium and preparation method thereof 云南中翼鼎东投资集团生物科技开发有限公司 2020-04-21 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4795621-A CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND SHIN NISSO KAKO CO., LTD. (JP) 1989-01-03 US claimed
EP-0175005-A1 5,6,7-Quinoline carbamates USV PHARMACEUTICAL CORPORATION (US) 1986-03-26 EP claimed
US-4547509-A TREATMENT OF HYPERTRIGLYCERIDEMIA USV PHARMACEUTICAL CORP. (US) 1985-10-15 US claimed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 US claimed
US-3986833-A TEST COMPOSITION, DEVICE, AND METHOD FOR THE DETECTION OF PEROXIDATIVELY ACTIVE SUBSTANCES MILES LABORATORIES, INC. (US) 1976-10-19 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed