SCHEMBL1236201

SCHEMBL1236201

CCCC1C=C(C(C)(C)C)C=C1c1c2c(ccc1=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1)=c1ccccc1=[C]2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1234537 0.81
Hydrochloric Acid SCHEMBL3269945 0.78 HDAC3 (0.32) ALDH1A1POLB
SCHEMBL3283802 0.73
SCHEMBL3277405 0.73 CNR2 (0.30)
SCHEMBL3273269 0.69 HDAC3 (0.30)
Hydrochloric Acid SCHEMBL1234386 0.66
Hydrochloric Acid SCHEMBL1235713 0.64 TAS1R3 (0.34) TAS1R3TAS1R1ALDH1A1POLB
Hydrochloric Acid SCHEMBL1235712 0.62 TAS1R3 (0.31) TAS1R3TAS1R1ALDH1A1POLB
SCHEMBL1234710 0.61
Hydrochloric Acid SCHEMBL1236427 0.61 TAS1R3 (0.33) TAS1R3TAS1R1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7879960-B2 methyl)(phenyl)methylene(3-tert-butyl-5-ethylcyclopentadienyl)(3,6-di-tert-butylfluorenyl)zirconium dichloride a metallocene], methylalumoxane, triisobutylaluminum containing catalyst system for propylene homo or copolymerization MITSUI CHEMICALS, INC. (JP) 2011-02-01 US disclosed
US-20080097055-A1 Process for Producing Propylene Polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
EP-1753731-A2 PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS Pharmacia Corporation (US) 2007-02-21 EP disclosed
WO-2004087677-A2 PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS PHARMACIA CORPORATION (US) 2004-10-14 WO disclosed