Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 1/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125016 | 0.83 | MEN1 (0.68) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL124716 | 0.83 | MAPT (0.73) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL30457465 | 0.81 | MEN1 (0.76) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL30457532 | 0.81 | MAPT (0.56) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL25228060 | 0.80 | MAPT (0.79) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL149619 | 0.79 | MEN1 (0.52) | MEN1KMT2AMAPTHSD17B10GAA | |
| SCHEMBL30457623 | 0.78 | MEN1 (0.77) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL144141 | 0.78 | MEN1 (0.45) | MEN1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL3054126 | 0.76 | HPGD (0.57) | MEN1KMT2AMAPTHSD17B10L3MBTL1 | |
| SCHEMBL1165628 | 0.75 | HPGD (0.55) | GRK5TYRO3DYRK1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051314-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | PARIS SCIENCES ET LETTRES (FR) | 2025-02-13 | — | — | US | disclosed |
| EP-4444308-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | Institut Curie (FR) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023104976-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | INSTITUT CURIE (FR) | 2023-06-15 | — | — | WO | disclosed |
| US-9873674-B2 | C-Rel inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160310716-A1 | Eyelid Margin Wipes Comprising Chemical Means for Temperature Adjustment | GUILLON, MICHEL (GB) | 2016-10-27 | — | — | US | disclosed |
| US-20160120693-A1 | Eye Care Devices and Methods | Optometric Technology Group (GB) | 2016-05-05 | — | — | US | disclosed |
| EP-2994083-A2 | EYE CARE DEVICES AND METHODS | Optometric Technology Group Ltd. (GB) | 2016-03-16 | — | — | EP | disclosed |
| US-20150218109-A1 | C-REL INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-08-06 | — | — | US | disclosed |
| WO-2014184677-A2 | EYE CARE DEVICES AND METHODS | OPTOMETRIC TECHNOLOGY GROUP LTD. (GB) | 2014-11-20 | — | — | WO | disclosed |
| US-20140142668-A1 | Eyelid Margin Wipes Comprising Chemical Means for Temperature Adjustment | OPTOMETRIC TECHNOLOGY GROUP LTD. (GB) | 2014-05-22 | — | — | US | disclosed |
| US-20060018953-A1 | Eyelid margin wipes comprising chemical means for temperature adjustment | OPTOMETRIC TECHNOLOGY GROUP LTD. (GB) | 2006-01-26 | — | — | US | disclosed |
| WO-2005023194-A2 | TEMPERATURE CHANGING SKIN CARE PRODUCT | PHYZZ, INC. (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20050048090-A1 | Temperature changing skin care product | TOWER LABORATORIES, LTD. | 2005-03-03 | — | — | US | disclosed |
| US-5869494-A | ADMINISTERING AS ANTITUMOR AGENTS, IMMUNE SYSTEM MODULATORS AND ANTIDEPRESSANTS | GULLIYA KIRPAL S (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0809634-A4 | NOVEL USES FOR BARBITURIC ACID ANALOGS | GULLIYA KIRPAL S (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0809634-A1 | NOVEL USES FOR BARBITURIC ACID ANALOGS | Gulliya, Kirpal S. (US) | 1997-12-03 | — | — | EP | disclosed |
| US-5674870-A | Anti-cancer uses for barbituric acid analogs | GULLIYA KIRPAL S (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1996025402-A1 | NOVEL USES FOR BARBITURIC ACID ANALOGS | GULLIYA KIRPAL S (US) | 1996-08-22 | — | — | WO | disclosed |
| US-4010872-A | OXIDATION HAIR DYE IN A PLURAL-FLUIDS DISPENSING PACKAGE | DART INDUSTRIES INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4004711-A | Disposable towel | GORHAM INTERNATIONAL INC. (US) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051314-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | STAT1, IFNG, IRF2BP2 | GRK5 1363/4885TYRO3 394/4885DYRK1B 3802/4885 |
| US-20150218109-A1 | C-REL INHIBITORS AND USES THEREOF | REL, NCOR1, CXCR4 | GRK5 1245/4885TYRO3 867/4885DYRK1B 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.