IFNG

Interferon gamma · P01579 · IFNG on Sugi Atlas →

653 patent compounds predicted against IFNG, 574 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL29399207 SCHEMBL29399207 0.49 2/20
SCHEMBL22360286 SCHEMBL22360286 0.49 2/20
SCHEMBL19731887 SCHEMBL19731887 0.48 2/20
1-Hexanol 1-Hexanol (SCHEMBL28255075) 0.47 2/20
SCHEMBL21179890 SCHEMBL21179890 0.47 2/20
SCHEMBL24067596 SCHEMBL24067596 0.46 2/20
Tetrabuthylammonium Tetrabuthylammonium (SCHEMBL28243195) 0.46 2/20
SCHEMBL28257936 SCHEMBL28257936 0.45 2/20
SCHEMBL18312441 SCHEMBL18312441 0.45 2/20
SCHEMBL18313211 SCHEMBL18313211 0.45 2/20
SCHEMBL21843053 SCHEMBL21843053 0.45 2/20
Water Water (SCHEMBL28083873) 0.45 2/20
SCHEMBL28313706 SCHEMBL28313706 0.45 2/20
Bromide Bromide (SCHEMBL28881717) 0.45 2/20
SCHEMBL29614646 SCHEMBL29614646 0.45 2/20
SCHEMBL18312573 SCHEMBL18312573 0.45 2/20
SCHEMBL18312865 SCHEMBL18312865 0.45 2/20
Cetylpyridinium Cetylpyridinium (SCHEMBL28131757) 0.45 2/20
SCHEMBL15616831 SCHEMBL15616831 0.44 2/20
SCHEMBL18373332 SCHEMBL18373332 0.44 2/20

Clinical trials — most relevant to IFNG by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of Allergen Immunotherapy on Anti-viral Immunity in Patients With Allergic Asthma PHASE4COMPLETED
Efficiency and Safety of the Drug Ingaron (Interferon-gamma Human Recombinant) in the Treatment of Chronic Prostatitis PHASE3COMPLETED
Study of the Efficacy and Safety of the Drug Ingaron (Interferon-gamma) in the Treatment of Anogenital Warts PHASE3COMPLETED
Observation on the Efficacy and Mechanism of SLIT With Dust Mite Allergen for PAR PHASE2/PHASE3UNKNOWN
Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients PHASE2UNKNOWN
Biomarker Study of PDR001 in Combination With MCS110 in Gastric Cancer PHASE2UNKNOWN
Treatment of Non-Tuberculous Mycobacterial Infections With Interferon Gamma PHASE2COMPLETED
ACTIMMUNE in Intermediate Osteopetrosis PHASE2COMPLETED
Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs PHASE2COMPLETED
Interferon Gamma-1b by Inhalation for the Treatment of Patients With Cystic Fibrosis PHASE1/PHASE2COMPLETED
Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis PHASE2COMPLETED
Mechanistic Study of Indigo Naturalis in Treating Psoriasis PHASE2COMPLETED
Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Malignant Melanoma PHASE2COMPLETED
A Pilot Trial of Interferon Beta-1a in Alzheimer's Disease PHASE2COMPLETED
Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Colitis PHASE2COMPLETED
Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer PHASE2WITHDRAWN
Interferon Gamma in Treating Patients With Recurrent or Metastatic Melanoma or Other Solid Tumors PHASE1COMPLETED
Effect of IFN-γ on Innate Immune Cells PHASE1COMPLETED
IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantation EARLY_PHASE1COMPLETED
Gene Expression Of Suppressor Of Cytokines in In Cutaneous Warts nanCOMPLETED
IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma nanCOMPLETED
Developing a Functional Cure for HIV Disease: Clinical Specimen Collection From HIV Positive Individuals nanUNKNOWN
Effect of SARS-CoV-2 Disease on Immune Responses, Disease Severity and Treatment Outcomes in Pulmonary Tuberculosis nanUNKNOWN
Kinetics of INF-γ Production in Intensive Care Patients nanRECRUITING
Comparison of the Human Papillomavirus (HPV) Type 16 E7-Specific Immune Response Between a Normal Population and Patients With Cervical Lesions nanUNKNOWN
Interleukin 4 and Interferon Gamma Predictors of Human Papillomavirus Immunotherapy in Warts nanCOMPLETED
The Development of Human Papillomavirus Type 16 E7-Specific Human Immunologic Assays in Non-HLA2 Type Human Being nanUNKNOWN
TGF β 1 Expression Related Gene Polymorphism nanRECRUITING
Long COVID Ultrasound Trial nanCOMPLETED
Role of the Host Immunity in the Non-response to Direct Anti-viral Agent (DAA) Therapy nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a IFNG binder may also engage these)

ProteinNameSimilarity
P42162 1.000 P42162 →
P63311 1.000 P63311 →
P63309 1.000 P63309 →
Q5I6S9 0.999 Q5I6S9 →
Q9TTB0 0.998 Q9TTB0 →
P79154 0.998 P79154 →
P63310 0.998 P63310 →
Q866Y6 0.996 Q866Y6 →
Q865Y4 0.996 Q865Y4 →
Q8MKF5 0.994 Q8MKF5 →
Q10420 0.994 Q10420 →
P28341 0.994 P28341 →
P07353 0.994 P07353 →
P28333 0.994 P28333 →
P34566 0.993 P34566 →
Q865W6 0.993 Q865W6 →
B9UJ97 0.993 B9UJ97 →
P01581 0.993 P01581 →
Q25BC0 0.993 Q25BC0 →
P42161 0.993 P42161 →
Q1ECV8 0.993 Q1ECV8 →
P17773 0.993 P17773 →
Q8SPW9 0.993 Q8SPW9 →
Q4ZH68 0.992 Q4ZH68 →
P22047 0.992 P22047 →
Q9KPU8 0.992 Q9KPU8 →
P01580 0.992 P01580 →
Q9CY02 0.992 Q9CY02 →
Q2PE75 0.992 Q2PE75 →
Q77GW1 0.992 Q77GW1 →