Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367252 | 0.86 | TSHR (0.49) | TSHR | |
| SCHEMBL679176 | 0.81 | TSHR (0.67) | TSHR | |
| SCHEMBL12367257 | 0.79 | TSHR (0.50) | TSHR | |
| SCHEMBL12367260 | 0.78 | TSHR (0.45) | TSHR | |
| SCHEMBL12367254 | 0.77 | TSHR (0.47) | TSHR | |
| SCHEMBL12367251 | 0.77 | TSHR (0.45) | TSHR | |
| SCHEMBL12367250 | 0.77 | TSHR (0.43) | TSHR | |
| SCHEMBL12367249 | 0.77 | TSHR (0.49) | TSHR | |
| SCHEMBL13573771 | 0.75 | TSHR (0.57) | TSHR | |
| SCHEMBL12367262 | 0.74 | ALDH1A1 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |