Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ethopropazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | BCHE | P06276 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | ACHE | P22303 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.97 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.97 |
| ▸ | HTR1A | P08908 | 4/20 | 0.97 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.97 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethopropazine SCHEMBL30516992 | 1.00 | ALDH1A1 (1.00) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL123702 | 1.00 | ALDH1A1 (1.00) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL10616920 | 0.98 | ALDH1A1 (0.97) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL29426328 | 0.98 | CYP2D6 (1.00) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL34046 | 0.98 | CYP2D6 (1.00) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL34045 | 0.98 | CYP2D6 (1.00) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL10626220 | 0.97 | ALDH1A1 (0.94) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL2316087 | 0.97 | CYP2D6 (0.97) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL719170 | 0.95 | CYP2D6 (0.94) | ALDH1A1BCHEALOX15HSD17B10ACHE | |
| Ethopropazine SCHEMBL6943819 | 0.94 | ALDH1A1 (0.89) | ALDH1A1BCHEALOX15HSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231536-A1 | CELECOXIB NANOCRYSTAL, PROCESS FOR PRODUCING CELECOXIB NANOCRYSTAL, PHARMACEUTICAL COMPOSITION, USE OF A CELECOXIB NANOCRYSTAL, AND METHOD OF TREATMENT FOR RELIEF OF PAIN- AND INFLAMMATION-RELATED CONDITIONS | ACHÉ LABORATÓRIOS FARMACÊUTICOS S.A. (BR) | 2025-11-13 | — | — | WO | claimed |
| WO-2025199660-A1 | THIONOCARBAMATE- AND LIGNIN-COLLECTING COMPOSITIONS | Oxiquim S.A. (CL) | 2025-10-02 | — | — | WO | claimed |
| WO-2025133713-A1 | SYSTEM FOR DIGITAL TRANSFER PRINTING ON LIGHT OR DARK TEXTILE SUBSTRATES AND TRANSFER METHOD | SUMIPRINT QUIMICA Y COLOR S.A.S. (CO) | 2025-06-26 | — | — | WO | claimed |
| WO-2025088241-A1 | HYBRID SOLID ELECTROLYTES AND METHOD OF PREPARATION THEREOF | BASQUE CENTER FOR MACROMOLECULAR DESIGN AND ENGINEERING, POLYMAT FUNDAZIOA (ES) | 2025-05-01 | — | — | WO | claimed |
| WO-2024249914-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING DYSTONIA | DUKE UNIVERSITY (US) | 2024-12-05 | — | — | WO | claimed |
| WO-2024164058-A1 | LIQUID BASE PRODUCT, LIQUID FORMULATED PRODUCT, LIQUID END PRODUCT, RENEWABLE AND BIODEGRADABLE FLEXIBLE POLYMER, PROCESS FOR MANUFACTURING A LIQUID BASE PRODUCT, PROCESS FOR MANUFACTURING A LIQUID FORMULATED PRODUCT, PROCESS FOR MANUFACTURING A LIQUID END PRODUCT, PROCESS FOR MANUFACTURING A RENEWABLE AND BIODEGRADABLE FLEXIBLE POLYMER | ISOCARE SOLUÇÕES AMBIENTAIS S/A (BR) | 2024-08-15 | — | — | WO | claimed |
| WO-2024113031-A1 | POLYETHYLENE TEREPHTHALATE-BASED ADHESIVE REPAIR PATCH FOR ANTI-CORROSIVE COATINGS, METHOD FOR PRODUCING SAME AND USE THEREOF | Petróleo Brasileiro S.A. - Petrobras (BR) | 2024-06-06 | — | — | WO | claimed |
| US-20240122859-A1 | EXTENDED RELEASE MULTIPLE UNIT PELLET SYSTEM COMPOSITION AND ITS PROCESS FOR THE PREPARATION | NOKHA TRADING LLP (IN) | 2024-04-18 | — | — | US | claimed |
| EP-4232004-A1 | FRACTAL FORMULATIONS | Nanogyre Sprl (BE) | 2023-08-30 | — | — | EP | claimed |
| EP-2349442-B1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE | UNIV TENNESSEE RES FOUND (US) | 2023-07-26 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| WO-2000021504-A1 | ENCAPSULATION OF SENSITIVE LIQUID COMPONENTS INTO A MATRIX TO OBTAIN DISCRETE SHELF-STABLE PARTICLES | GENERAL MILLS, INC. (US) | 2000-04-20 | — | — | WO | claimed |
| EP-0935523-A4 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GEN MILLS INC (US) | 1999-12-29 | — | — | EP | claimed |
| EP-0935523-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GENERAL MILLS, INC. (US) | 1999-08-18 | — | — | EP | claimed |
| WO-1998018610-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | LENGERICH BERNHARD H VAN (US) | 1998-05-07 | — | — | WO | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5192550-A | Dosage form for treating central nervous system disorders | ALZA CORPORATION (US) | 1993-03-09 | — | — | US | claimed |