Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.37 |
| ▸ | TK2 | O00142 | 5/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18286616 | 0.96 | TYMP (0.40) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL9908655 | 0.95 | TYMP (0.38) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL18286621 | 0.95 | TYMP (0.39) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL12371805 | 0.94 | TYMP (0.41) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL30733464 | 0.92 | TYMP (0.38) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL30733474 | 0.92 | TYMP (0.38) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL4081765 | 0.92 | TK2 (0.43) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL30733450 | 0.89 | TYMP (0.38) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL30733458 | 0.89 | TYMP (0.38) | TYMPP2RY14TK2P2RY12P2RY2 | |
| SCHEMBL30733456 | 0.89 | TYMP (0.36) | TYMPP2RY14TK2P2RY12P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005861-A9 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011005861-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |