Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 5/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371804 | 0.92 | TYMP (0.40) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL18286616 | 0.92 | TYMP (0.40) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL12371805 | 0.91 | TYMP (0.41) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL18286621 | 0.90 | TYMP (0.39) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL30733450 | 0.89 | TYMP (0.38) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL30733464 | 0.89 | TYMP (0.38) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL9908655 | 0.89 | TYMP (0.38) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL30733474 | 0.89 | TYMP (0.38) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL30733458 | 0.89 | TYMP (0.38) | TK2TYMPP2RY14P2RY12P2RY2 | |
| SCHEMBL26502740 | 0.88 | TYMP (0.47) | TYMPP2RY14P2RY12P2RY2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | ANXA6, STING1, POLRMT | TK2 760/4885TYMP 2413/4885P2RY14 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.