SCHEMBL1237207

SCHEMBL1237207

O=C1c2cc([N+](=O)[O-])ccc2-c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 0.91
S100A4 P26447 2/20 0.91
BCHE P06276 1/20 0.78
ACHE P22303 1/20 0.78
CES1 P23141 1/20 0.78
CYP1A2 P05177 2/20 0.73
HIF1A Q16665 2/20 0.73
HSD17B10 Q99714 2/20 0.73
TDP1 Q9NUW8 2/20 0.62
ALDH1A1 P00352 2/20 0.62
CYP3A4 P08684 2/20 0.62
MAPT P10636 3/20 0.62
KDM4E B2RXH2 1/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
MCL1 Q07820 1/20 0.60
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30349970 1.00 PTPRC (0.91) PTPRCS100A4BCHEACHECES1
SCHEMBL30375977 0.96 PTPRC (0.84) PTPRCS100A4BCHEACHECES1
SCHEMBL8104719 0.96 PTPRC (0.84) PTPRCS100A4BCHEACHECES1
SCHEMBL2772220 0.95 PTPRC (0.83) PTPRCS100A4BCHEACHECES1
SCHEMBL2599382 0.95 PTPRC (1.00) PTPRCS100A4BCHEACHECES1
SCHEMBL11207794 0.95 PTPRC (0.83) PTPRCS100A4BCHEACHECES1
SCHEMBL29559206 0.95 PTPRC (1.00) PTPRCS100A4BCHEACHECES1
SCHEMBL229511 0.92 PTPRC (0.93) PTPRCS100A4BCHEACHECES1
SCHEMBL31615476 0.92 PTPRC (0.93) PTPRCS100A4BCHEACHECES1
SCHEMBL8091665 0.91 PTPRC (0.78) PTPRCS100A4BCHEACHECES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409495-A1 PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-12-12 US claimed
CN-116355434-B Method for preparing direct dye by replacing benzidine 广东省科学院测试分析研究所(中国广州分析测试中心) 2024-07-09 CN claimed
CN-118175999-A Process for the preparation of 2, 7-dihydroxy-9-fluorenone useful for the synthesis of telulone and its salts 科学与工业研究委员会 2024-06-11 CN claimed
CN-116355434-A Method for preparing direct dye by replacing benzidine 广东省科学院测试分析研究所(中国广州分析测试中心) 2023-06-30 CN claimed
WO-2023067624-A1 A PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-04-27 WO claimed
CN-103936686-B N-semiaromatic alkyl diamine-bisphenol type four degree of functionality fluorenyl benzoxazine and preparation methods HARBIN ENGINEERING UNIV. (CN) 2016-05-04 CN claimed
US-20110262845-A1 METHOD FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITION WITHOUT EXTERNAL BIAS VOLTAGE NITTO DENKO CORPORATION 2011-10-27 US claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
WO-2010047904-A1 METHOD FOR MODULATING LIGHT OF PHOTORE-FRACTIVE COMPOSITION WITHOUT EXTERNAL BIAS VOLTAGE NITTO DENKO CORPORATION (JP) 2010-04-29 WO claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
CN-1096096-C CRT electrophotographic screening method using an organic photoconductor RCA THOMSON LICENSING CORP (US) 2002-12-11 CN claimed
US-6340528-B1 USEFUL IN IONOGRAPHIC OR ELECTROPHOTOGRAPHIC APPARATUSES AND USEFUL IN HYBRID SCAVENGELESS DEVELOPMENT UNITS XEROX CORPORATION 2002-01-22 US claimed
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed
EP-0315140-B1 Non-linear optical device HITACHI LTD (JP) 1995-08-23 EP claimed
US-5413885-A Organic photoconductor for an electrophotographic screening process for a CRT RCA THOMPSON LICENSING CORP. (US) 1995-05-09 US claimed
EP-0037902-B1 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1986-06-18 EP claimed
US-4591542-A CONTAINING AMINE COMPOUND IN CHARGE GENERATING PHASE IN LOWER CONCENTRATIONS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-05-27 US claimed
EP-0130687-A2 Light-sensitive member and preparation thereof KONICA CORPORATION (JP) 1985-01-09 EP claimed
US-4338222-A Semiconductive organic compositions XEROX CORPORATION (US) 1982-07-06 US claimed
US-4302521-A TRANSPORT PHASE OF A P-TYPE ORGANIC SEMICONDUCTOR, POLYVINYLCARBAZOLE, A LEWIS AND A BRONSTED ACID; CHARGE TRANSFER COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-11-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409495-A1 PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS TALDO1, TKFC, DHCR7 PTPRC 1715/4885S100A4 3294/4885BCHE 3038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.