SCHEMBL12373453

SCHEMBL12373453

CCCCNc1nc(NCCCCN)nc(NCCCCN)n1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 7/20 0.51
KCNH3 Q9ULD8 2/20 0.50
KMT2A Q03164 2/20 0.50
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
SLC29A1 Q99808 1/20 0.47
DNM2 P50570 1/20 0.42
DNM1 Q05193 3/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12373455 0.94 KMT2A (0.57) TLR8KCNH3KMT2ADNM2DNM1
SCHEMBL9913709 0.89 CA1 (0.49) TLR8KCNH3KMT2ACA1CA2
SCHEMBL16769809 0.89 CA1 (0.49) TLR8KCNH3KMT2ACA1CA2
SCHEMBL1274316 0.89 CA12 (0.46) TLR8KCNH3KMT2ACA1CA2
SCHEMBL1273822 0.87 CA12 (0.45) TLR8KCNH3KMT2ACA1CA2
SCHEMBL1272863 0.87 CA12 (0.45) TLR8KCNH3KMT2ACA1CA2
SCHEMBL2784426 0.87 SLC29A1 (0.57) TLR8KCNH3KMT2ACA1CA2
SCHEMBL11796047 0.86 KMT2A (0.50) TLR8KCNH3KMT2ADNM2DNM1
SCHEMBL12712379 0.85 KMT2A (0.53) TLR8KCNH3KMT2ADNM2DNM1
SCHEMBL7774845 0.85 KMT2A (0.65) KCNH3KMT2ACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8007546-B2 Treating polyamide fibers before, during or after dyeing with a liquor comprising a derivative of diamino-1,3,5-triazine, triamino-1,3,5-triazine, diaminohalo-1,3-5-triazine, or diaminooxy-1,3,5-triazine; colorfastness HUNTSMAN INTERNATIONAL LLC (US) 2011-08-30 US disclosed
US-8007546-B2 Treating polyamide fibers before, during or after dyeing with a liquor comprising a derivative of diamino-1,3,5-triazine, triamino-1,3,5-triazine, diaminohalo-1,3-5-triazine, or diaminooxy-1,3,5-triazine; colorfastness HUNTSMAN INTERNATIONAL LLC (US) 2011-08-30 US disclosed
US-20080178395-A1 Method of Increasing Depth Shade HUNTSMAN INTERNATIONAL LLC. (TX) 2008-07-31 US disclosed
US-20080178395-A1 Method of Increasing Depth Shade HUNTSMAN INTERNATIONAL LLC. (TX) 2008-07-31 US disclosed