SCHEMBL1272863

SCHEMBL1272863

NCCCCCCNc1nc(NCCCCCCN)nc(NCCCCCCN)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.45
CA1 P00915 5/20 0.45
CA2 P00918 5/20 0.45
CA9 Q16790 5/20 0.45
NPY1R P25929 1/20 0.44
NPY5R Q15761 1/20 0.44
KMT2A Q03164 1/20 0.43
CA3 P07451 3/20 0.42
CA4 P22748 3/20 0.42
CA6 P23280 3/20 0.42
CA5A P35218 3/20 0.42
CA7 P43166 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA5B Q9Y2D0 3/20 0.42
KCNH3 Q9ULD8 3/20 0.42
TSHR P16473 2/20 0.42
F13A1 P00488 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1273822 1.00 CA12 (0.45) CA12CA1CA2CA9NPY1R
SCHEMBL1274316 0.97 CA12 (0.46) CA12CA1CA2CA9NPY1R
SCHEMBL4163258 0.91 TLR8 (0.46) CA12CA1CA2CA9NPY1R
SCHEMBL1273829 0.90 CA12 (0.51) CA12CA1CA2CA9NPY1R
SCHEMBL12373454 0.89 KMT2A (0.41) CA12CA1CA2CA9NPY1R
SCHEMBL12373450 0.89 KMT2A (0.57) CA12CA1CA2CA9NPY1R
SCHEMBL12373451 0.89 KMT2A (0.57) CA12CA1CA2CA9NPY1R
SCHEMBL12373455 0.89 KMT2A (0.57) KMT2AKCNH3TSHRDNM1TLR8
SCHEMBL21449078 0.89 HTR7 (0.46) CA12CA1CA2CA9NPY1R
SCHEMBL11794554 0.89 TLR8 (0.42) CA12CA1CA2CA9NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12010996-B2 Tris-substituted biguanide compounds and their uses CHEN HWANG HSING (US) 2024-06-18 US claimed
US-20130224496-A1 High Hardness Low Surface Energy Coating HARDCOAT SURFACES LLC (US) 2013-08-29 US claimed
WO-2012058657-A2 HIGH HARDNESS LOW SURFACE ENERGY COATING HARDCOAT SURFACES LLC (US) 2012-05-03 WO claimed
EP-1247837-B1 Modified amino resins for semifinished products and molded bodies having an improved resilience AMI AGROLINZ MELAMINE INT GMBH (AT) 2008-05-14 EP claimed
US-7208540-B2 Process for curing aminoplast resins AGROLINZ MELAMIN GMBH (AT) 2007-04-24 US claimed
US-7196131-B2 Polymer-modified inorganic particles AGROLINZ MELAMIN GMBH (AT) 2007-03-27 US claimed
EP-1341856-B1 POLYMER MODIFIED INORGANIC PARTICLES AMI AGROLINZ MELAMINE INT GMBH (AT) 2006-09-20 EP claimed
EP-1341846-B1 METHOD FOR CURING AMINOPLAST RESINS AMI AGROLINZ MELAMINE INT GMBH (AT) 2006-08-02 EP claimed
US-7012108-B2 Multilayer structure; overcoating filler with amino resin AGROLINZ MELAMIN GMBH (AT) 2006-03-14 US claimed
US-20050020750-A1 Method for curing aminoplast resins AGROLINZ MELAMIN GMBH (AT) 2005-01-27 US claimed
US-20040082697-A1 Multilayer structure; overcoating filler with amino resin AGROLINZ MELAMIN GMBH (AT) 2004-04-29 US claimed
US-20040054034-A1 Polymer-modified inorganic particles AGROLINZ MELAMIN GMBH (AT) 2004-03-18 US claimed
EP-1353994-A2 MODIFIED INORGANIC PARTICLES AMI Agrolinz Melamine International GmbH (AT) 2003-10-22 EP claimed
EP-1341856-A1 POLYMER MODIFIED INORGANIC PARTICLES Agrolinz Melamin GmbH (AT) 2003-09-10 EP claimed
EP-1341846-A2 METHOD FOR CURING AMINOPLAST RESINS Agrolinz Melamin GmbH (AT) 2003-09-10 EP claimed
EP-1247837-A2 Modified amino resins for semifinished products and molded bodies having an improved resilience Agrolinz Melamin GmbH (AT) 2002-10-09 EP claimed
WO-2002048248-A2 MODIFIED INORGANIC PARTICLES AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
WO-2002048270-A1 POLYMER MODIFIED INORGANIC PARTICLES AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
WO-2002048261-A2 METHOD FOR CURING AMINOPLAST RESINS AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
US-4980404-A CARBOXYL CONTAINING POLYACRYLATE AND POLYAMINE COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1990-12-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12010996-B2 Tris-substituted biguanide compounds and their uses PUF60, KCNN1, XRCC6 CA12 2845/4885CA1 1746/4885CA2 1824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.