SCHEMBL12374344

SCHEMBL12374344

CCOC(=O)c1cc(C2(c3ccc(OC)c(C(=O)OCC)c3)c3cc(C)ccc3-c3ccc(C)cc32)ccc1OC

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.42
MAPT P10636 4/20 0.42
HPGD P15428 1/20 0.41
ERN1 O75460 1/20 0.41
HSD17B2 P37059 1/20 0.40
ALDH1A1 P00352 2/20 0.40
CDC25B P30305 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
POLB P06746 2/20 0.39
TSHR P16473 1/20 0.39
DPP4 P27487 1/20 0.39
GAA P10253 5/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KCNK3 O14649 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374348 0.91 ERN1 (0.42) LMNAMAPTHPGDERN1HSD17B2
SCHEMBL13400898 0.88 HSP90AA1 (0.44) LMNAMAPTHPGDALDH1A1GAA
SCHEMBL13494970 0.85 PTPN11 (0.41) LMNAMAPTHPGDALDH1A1SMN1; SMN2
SCHEMBL13400867 0.85 PTPN11 (0.41) LMNAMAPTHPGDALDH1A1SMN1; SMN2
SCHEMBL10348289 0.85 MEN1 (0.42) LMNAMAPTHPGDALDH1A1SMN1; SMN2
SCHEMBL13400900 0.84 HTT (0.39) LMNAMAPTHPGDALDH1A1SMN1; SMN2
SCHEMBL13494976 0.84 ALDH1A1 (0.41) MAPTHPGDALDH1A1SMN1; SMN2TDP1
SCHEMBL13400897 0.84 MAPT (0.43) LMNAMAPTALDH1A1SMN1; SMN2TSHR
SCHEMBL13400896 0.84 MAPT (0.43) LMNAMAPTALDH1A1SMN1; SMN2TSHR
SCHEMBL14929147 0.83 MEN1 (0.35) HPGDALDH1A1SMN1; SMN2TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 US disclosed
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-12-27 US disclosed
US-20110187266-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CCNA1, CCNB1, CCNL2 LMNA 668/4885MAPT 3485/4885HPGD 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.