Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26543052 | 0.92 | TLR4 (0.43) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL2282040 | 0.84 | MAOA (0.54) | TDP1TLR4TLR2FURINNPC1 | |
| SCHEMBL412110 | 0.81 | KMT2A (0.50) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL412094 | 0.80 | TLR4 (0.60) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL30023543 | 0.80 | NPC1 (0.45) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL1985566 | 0.80 | NPC1 (0.45) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL7992660 | 0.80 | FURIN (0.43) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL10071523 | 0.79 | FURIN (0.50) | TDP1TP53TLR4TLR2CHRNA7 | |
| SCHEMBL2623207 | 0.79 | TSHR (0.57) | TLR4TLR2KMT2A | |
| SCHEMBL10071513 | 0.79 | MAPK1 (0.49) | TDP1TP53TLR4TLR2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4047417-B1 | CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2023-08-16 | — | — | EP | disclosed |
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |