SCHEMBL12375042

SCHEMBL12375042

C=C(C)C(=O)Cc1cc2ccc(CCC(=O)Oc3ccc(COC(=O)C(=C)C)cc3)c(F)c2c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375045 0.80 MAPT (0.41) KMT2AKDM4EALDH1A1
SCHEMBL13963266 0.79
SCHEMBL12375046 0.76 MAPT (0.38) KMT2AKDM4EMEN1ALDH1A1TSHR
SCHEMBL12375027 0.75 KMT2A (0.43) KMT2AMEN1ALDH1A1
SCHEMBL12375060 0.73 KMT2A (0.46) KMT2AKDM4EMEN1ALDH1A1TSHR
SCHEMBL13963275 0.70 PTGER3 (0.32)
SCHEMBL13963301 0.70 PTGS1 (0.30)
SCHEMBL13963250 0.70 AKR1B10 (0.34) KMT2AKDM4EMEN1
SCHEMBL19194552 0.69 ELANE (0.47) KMT2AKDM4EMEN1ALDH1A1
SCHEMBL12375031 0.69 AKR1C3 (0.35) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8440101-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC CORPORATION (JP) 2013-05-14 US disclosed
US-20110186776-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2011-08-04 US disclosed