SCHEMBL12375044

SCHEMBL12375044

C=C(C)C(=O)COc1ccc2cc(CCC(=O)Oc3ccc(OCOC(=O)C(=C)C)cc3)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAOA P21397 1/20 0.41
SLC6A2 P23975 1/20 0.41
RAB9A P51151 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 2/20 0.37
DHODH Q02127 2/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AKR1C3 P42330 1/20 0.33
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375048 0.93 MAPT (0.37) MAPTKDM4ENPC1LMNATP53
SCHEMBL12375054 0.92 KMT2A (0.37) MAPTKDM4ENPC1LMNATP53
SCHEMBL12375034 0.92 KMT2A (0.44) MAPTLMNAKMT2APOLBAPEX1
SCHEMBL12375021 0.89 KMT2A (0.42) MAPTLMNAKMT2APOLBAPEX1
SCHEMBL12375081 0.80 MAPT (0.52) MAPTKDM4ENPC1LMNATP53
SCHEMBL11986159 0.80 KMT2A (0.43) MAPTLMNAKMT2APOLBAPEX1
SCHEMBL12242549 0.79 AKR1C3 (0.34) MAPTKDM4ENPC1LMNATP53
SCHEMBL12375045 0.79 MAPT (0.41) MAPTKDM4ENPC1LMNATP53
SCHEMBL12242492 0.78 FFAR1 (0.40) KDM4ETP53RAB9AKMT2APOLB
SCHEMBL13963230 0.78 KMT2A (0.36) MAPTKDM4ELMNASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8440101-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC CORPORATION (JP) 2013-05-14 US disclosed
US-20110186776-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2011-08-04 US disclosed