SCHEMBL12375021

SCHEMBL12375021

C=C(C)C(=O)COc1ccc(-c2ccc(CCC(=O)Oc3ccc(OCOC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
FFAR1 O14842 2/20 0.37
POLB P06746 2/20 0.36
HTT P42858 2/20 0.36
APEX1 P27695 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 4/20 0.34
MAPT P10636 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GAA P10253 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375034 0.97 KMT2A (0.44) KMT2AFFAR1POLBHTTAPEX1
SCHEMBL12375054 0.93 KMT2A (0.37) KMT2AFFAR1POLBHTTAPEX1
SCHEMBL12375048 0.92 MAPT (0.37) KMT2AFFAR1POLBHTTAPEX1
SCHEMBL12375044 0.89 MAPT (0.41) KMT2APOLBHTTAPEX1TDP1
SCHEMBL16425296 0.86 MAPT (0.43) KMT2AFFAR1POLBMAPTALDH1A1
SCHEMBL11986159 0.84 KMT2A (0.43) KMT2APOLBHTTAPEX1TDP1
SCHEMBL16425368 0.82 KMT2A (0.43) KMT2AFFAR1POLBHTTAPEX1
SCHEMBL12375024 0.82 THRB (0.43) KMT2AFFAR1MAPTGAA
SCHEMBL17433325 0.81 KMT2A (0.54) KMT2AFFAR1HTTLMNAMAPT
SCHEMBL12242494 0.80 FFAR1 (0.41) FFAR1POLBHTTAPEX1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8440101-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC CORPORATION (JP) 2013-05-14 US disclosed
US-20110186776-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2011-08-04 US disclosed