Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12375020 | 0.93 | THRB (0.43) | THRBFFAR1KMT2AAKR1B1FFAR4 | |
| SCHEMBL15582417 | 0.87 | THRB (0.49) | THRBFFAR1KMT2AAKR1B1FFAR4 | |
| SCHEMBL12154277 | 0.86 | THRB (0.38) | THRBFFAR1KMT2AMAPTNFKB1 | |
| SCHEMBL12154247 | 0.85 | THRB (0.48) | THRBPDGFRBPDGFRAFFAR1KMT2A | |
| SCHEMBL17754262 | 0.85 | THRB (0.39) | THRBKMT2AFFAR4MAPTHSD17B1 | |
| SCHEMBL12242523 | 0.85 | THRB (0.41) | THRBFFAR1KMT2AFFAR4HPGD | |
| SCHEMBL12154226 | 0.83 | THRB (0.52) | THRBFFAR1KMT2AFFAR4MAPT | |
| SCHEMBL16425374 | 0.81 | THRB (0.47) | THRBFFAR1KMT2AFFAR4MAPT | |
| SCHEMBL13963241 | 0.81 | KMT2A (0.35) | THRBKMT2AMAPT | |
| SCHEMBL13963253 | 0.80 | KMT2A (0.36) | THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440101-B2 | Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same | DIC CORPORATION (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20110186776-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2011-08-04 | — | — | US | disclosed |