Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12242814 | 0.83 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL12375024 | 0.83 | THRB (0.43) | MAPTTHRBMEN1KMT2AFFAR1 | |
| SCHEMBL15582433 | 0.81 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL17754347 | 0.79 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL15582432 | 0.79 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL12375059 | 0.79 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL17461526 | 0.79 | THRB (0.50) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL12375056 | 0.79 | ESR1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL12242705 | 0.78 | THRB (0.40) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL18328845 | 0.77 | NPC1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440101-B2 | Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same | DIC CORPORATION (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20110186776-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2011-08-04 | — | — | US | disclosed |