SCHEMBL123763

SCHEMBL123763

CC(C)(c1ccccc1)c1cc(O)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.59
ALDH1A1 P00352 6/20 0.59
ESR2 Q92731 5/20 0.59
HSD17B10 Q99714 3/20 0.59
ALOX15 P16050 3/20 0.59
CYP3A4 P08684 2/20 0.59
TYR P14679 2/20 0.59
NR1I2 O75469 1/20 0.59
LMNA P02545 1/20 0.59
CYP2C9 P11712 1/20 0.59
MIF P14174 1/20 0.59
HTT P42858 1/20 0.59
NFE2L2 Q16236 1/20 0.59
TSHR P16473 2/20 0.45
HPGD P15428 2/20 0.45
AR P10275 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
HTR6 P50406 1/20 0.45
ESRRG P62508 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29490659 1.00 ESR1 (0.59) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL4055230 0.88 ALDH1A1 (0.63) ESR1ALDH1A1ESR2HSD17B10ALOX15
Vinyl Ether SCHEMBL5025774 0.87 ESR1 (0.46) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL18635219 0.87 ESR1 (0.69) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL18635220 0.87 ESR1 (0.69) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL8085234 0.87 ALDH1A1 (0.57) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL29290927 0.86 ESR2 (0.61) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL9249881 0.86 ESR1 (0.56) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL23861363 0.85 ALDH1A1 (0.59) ESR1ALDH1A1ESR2HSD17B10ALOX15
SCHEMBL9815465 0.85 ALDH1A1 (0.59) ESR1ALDH1A1ESR2HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2741 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114276530-A Intermittent phosgene interface method preparation process of polycarbonate and application thereof 深圳市德力塑化工科技有限公司 2022-04-05 CN claimed
EP-2084226-B1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-02-27 EP claimed
US-8114952-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-02-14 US claimed
US-8106126-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-31 US claimed
EP-2288661-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-03-02 EP claimed
EP-2285903-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-02-23 EP claimed
US-7691304-B2 Transparant blend of an aromatic polyester, and an aromatic polycarbonate; transparent covers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-04-06 US claimed
US-7686998-B2 Blend of an aromatic polyester, and an aromatic polycarbonate; transparent covers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-30 US claimed
US-7655737-B2 Blend of polycarbonate comprising 10-90 mole percent acrylate units and polyester; improved toughness, impact strength; improvements retained after heat aging or at low temperatures, and obtained without having detrimental effect on other desirable properties such as transparency SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-02 US claimed
US-20090286921-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
US-5013819-A Units from aromatic or cycloaliphatic dicarboxy acid and from a mixture of mono-aralkyl substituted hydroquinones, matrix fo r composite material MONTEDISON S.P.A. (IT) 1991-05-07 US claimed
US-4966957-A Liquid-crystalline, thermotropic aromatic polyester from hydroquinone mixture MONTEDISON S.P.A. (IT) 1990-10-30 US claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
US-4923955-A Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
EP-0337133-A1 Liquid-crystalline, thermotropic polymers of di-s-triazines HIMONT ITALIA S.r.l. (IT) 1989-10-18 EP claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
EP-0323126-A2 Liquid-crystalline, thermotropic aromatic polyesters Montedison S.p.A. (IT) 1989-07-05 EP claimed
EP-0321107-A1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-21 EP claimed
EP-0320298-A2 Liquid-crystalline, thermotropic aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-14 EP claimed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed