SCHEMBL12376691

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12603632	0.79	ELANE (0.64)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL10170649	0.78	ELANE (0.67)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL92378	0.77	ELANE (0.66)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL24196288	0.77	ELANE (0.43)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL19431469	0.76	KMT2A (0.50)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL13963884	0.75	ALDH1A1 (0.43)	POLBKMT2AHTTSMN1; SMN2TDP1
	SCHEMBL12220345	0.75	HTT (0.49)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL12220348	0.74	ELANE (0.54)	ELANEPOLBKMT2AHTTSMN1; SMN2
	SCHEMBL9186604	0.73	ELANE (0.52)	ELANEPOLBKMT2ASMN1; SMN2TDP1
	SCHEMBL24595910	0.73	ELANE (0.53)	ELANEPOLBKMT2AHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.