Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380534 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24686939 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24686272 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24686941 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24687404 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24686268 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24686927 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24687409 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL24687310 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 | |
| SCHEMBL27229081 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDHTTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998726-B2 | Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2011-08-16 | — | — | US | disclosed |