SCHEMBL12376959

SCHEMBL12376959

COc1ccc(C(C)(C)c2ccc(OC(=O)c3ccc(Oc4ccc(C(C)=O)cc4)cc3)c(C)c2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.47
MAPT P10636 4/20 0.45
RAB9A P51151 2/20 0.45
HPGD P15428 1/20 0.45
GAA P10253 1/20 0.43
ESRRA P11474 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12404390 1.00 KMT2A (0.47) KMT2AMAPTRAB9AHPGDGAA
SCHEMBL19500463 0.96 KMT2A (0.44) KMT2AMAPTRAB9AHPGDGAA
SCHEMBL12345970 0.94 KMT2A (0.46) KMT2AMAPTGAATDP1ALDH1A1
SCHEMBL12404394 0.92 KMT2A (0.44) KMT2AMAPTHPGDGAATDP1
SCHEMBL17716493 0.92 KMT2A (0.44) KMT2AMAPTRAB9AGAATDP1
SCHEMBL12445348 0.90 KMT2A (0.43) KMT2AMAPTGAATDP1ALDH1A1
SCHEMBL15249585 0.89 KMT2A (0.52) KMT2AMAPTRAB9AHPGDGAA
SCHEMBL18591534 0.89 KMT2A (0.44) KMT2AMAPTRAB9AHPGDGAA
SCHEMBL18591533 0.89 KMT2A (0.44) KMT2AMAPTRAB9AHPGDGAA
SCHEMBL13324844 0.89 KMT2A (0.46) KMT2AMAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9811008-B2 Image forming method, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-9766561-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-19 US disclosed
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-9684277-B2 Process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-20170060008-A1 IMAGE FORMING METHOD, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 US disclosed
US-9575422-B2 Method of producing electrophotographic photosensitive member, method of producing organic device, and emulsion for charge transporting layer CANON KABUSHIKI KAISHA (JP) 2017-02-21 US disclosed
US-9557660-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, charge transport layer forming coating liquid, and method for manufacturing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2017-01-31 US disclosed
US-20170010556-A1 IMAGE FORMING METHOD, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-01-12 US disclosed
US-9529284-B2 Process cartridge, image forming method, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-12-27 US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 US disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed
US-7655370-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-02-02 US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080304864-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-12-11 US disclosed
US-7413840-B1 Process for forming an electrophotographic photosensitive member with depressed portions by condensing a surface of a surface layer on which a coating liquid is present CANON KABUSHIKI KAISHA (JP) 2008-08-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed