SCHEMBL12377232

SCHEMBL12377232

CCNCC(C)C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CC(C)CNCC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10120038 0.93
SCHEMBL13150392 0.92 KDM4E (0.34) KDM4E
SCHEMBL16084555 0.82
SCHEMBL19130080 0.79
SCHEMBL12588607 0.78
SCHEMBL4782503 0.76 KDM4E (0.33) KDM4E
SCHEMBL9716544 0.76 KDM4E (0.32) KDM4E
SCHEMBL113604 0.73 KDM4E (0.33) KDM4E
SCHEMBL19477973 0.72 KDM4E (0.35) KDM4E
SCHEMBL12891508 0.72 KDM4E (0.35) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139753-B2 Single-component moisture-curable coatings based on N-substituted urea polymers with extended chains and terminal alkoxysilanes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-22 US disclosed
US-20140275405-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2014-09-18 US disclosed
US-20110190455-A1 POLYDIALKYLSILOXANE-BRIDGED BI-PHOTOCHROMIC MOLECULES Vivimed Labs Europe Ltd. (GB) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190455-A1 POLYDIALKYLSILOXANE-BRIDGED BI-PHOTOCHROMIC MOLECULES UACA, DCLRE1A, RAD54L KDM4E 3162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.