SCHEMBL12377657

SCHEMBL12377657

Cc1ccc(N=Nc2c(SOOO)cc3cc(Nc4nc(Cl)nc(Cl)n4)ccc3c2O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 3/20 0.53
▸ CARM1 Q86X55 1/20 0.53
▸ APP P05067 2/20 0.38
▸ NFKB1 P19838 3/20 0.37
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ CYP1A2 P05177 2/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ ENPP2 Q13822 3/20 0.33
▸ PHLPP2 Q6ZVD8 1/20 0.33
▸ RAB9A P51151 1/20 0.32
▸ SLC2A1 P11166 1/20 0.32
▸ TERT O14746 1/20 0.32
▸ PRMT3 O60678 1/20 0.32
▸ EP300 Q09472 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13599503 0.92 PRMT1 (0.46) PRMT1CARM1APPNFKB1MEN1
SCHEMBL14362772 0.87 PRMT1 (0.56) PRMT1CARM1NFKB1MEN1KMT2A
SCHEMBL13088656 0.85 PHLPP2 (0.38) PRMT1CARM1MEN1KMT2ANPC1
SCHEMBL11911530 0.82 CYP1A2 (0.39) MEN1KMT2ANPC1CYP1A2CYP2C9
SCHEMBL12052812 0.81 PRMT1 (0.50) PRMT1CARM1ENPP2PHLPP2PRMT3
SCHEMBL12377654 0.81 PRMT1 (0.49) PRMT1CARM1NFKB1NPC1CYP1A2
SCHEMBL13860892 0.80 PRMT1 (0.40) PRMT1CARM1ENPP2PHLPP2PRMT3
SCHEMBL14362776 0.80 PRMT1 (0.48) PRMT1CARM1NFKB1MEN1KMT2A
SCHEMBL13088659 0.80 ENPP2 (0.39) PRMT1CARM1MEN1KMT2ANPC1
SCHEMBL13387299 0.80 FUT8 (0.43) PRMT1CARM1APPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003590-B2 Detergent composition comprising reactive dye THE PROCTER & GAMBLE COMPANY (US) 2011-08-23 — — US disclosed
US-7829517-B2 Detergent composition comprising non-ionic detersive surfactant mixture and reactive dye mixture THE PROCTER & GAMBLE COMPANY (US) 2010-11-09 — — US disclosed
US-7745385-B2 Water-soluble pouch comprising a detergent composition THE PROCTER & GAMBLE COMPANY (US) 2010-06-29 — — US disclosed
US-7632316-B2 Reactive dyestuff, method for production thereof and use of the same DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-12-15 — — US disclosed
US-20090253604-A1 Water-Soluble Pouch Comprising a Detergent Composition THE PROCTER & GAMBLE COMPANY 2009-10-08 — — US disclosed
US-20090253606-A1 Detergent Composition Comprising Non-Ionic Detersive Surfactant and Reactive Dye THE PROCTER & GAMBLE COMPANY 2009-10-08 — — US disclosed
US-20090253607-A1 Detergent Composition Comprising Reactive Dye THE PROCTER & GAMBLE COMPANY 2009-10-08 — — US disclosed
US-20090249561-A1 Kit of Parts Comprising a Solid Laundry Detergent Composition and a Dosing Device THE PROCTER & GAMBLE COMPANY 2009-10-08 — — US disclosed
US-20080189880-A1 Reactive Dyestuff, Method For Production Thereof and Use of the Same DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-08-14 — — US disclosed
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