Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.80 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378928 | 0.89 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL2355220 | 0.87 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL2355016 | 0.85 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL12378887 | 0.85 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL12417590 | 0.85 | NR3C1 (0.86) | NR3C1PGRAR | |
| SCHEMBL12417266 | 0.83 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL12378884 | 0.83 | NR3C1 (0.81) | NR3C1PGRAR | |
| SCHEMBL2355721 | 0.81 | NR3C1 (0.73) | NR3C1PGRAR | |
| SCHEMBL12378888 | 0.81 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL12378940 | 0.80 | NR3C1 (0.73) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994190-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-08-09 | — | — | US | disclosed |