Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 17/20 | 0.71 |
| ▸ | CDK2 | P24941 | 4/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.71 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | PI4KA | P42356 | 1/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611365 | 0.83 | CDK1 (1.00) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL756644 | 0.83 | CDK1 (1.00) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL784159 | 0.81 | CDK2 (0.73) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL2314138 | 0.80 | CDK1 (0.55) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL22700170 | 0.80 | CDK1 (0.71) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL24235899 | 0.80 | CDK2 (0.71) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL3441256 | 0.80 | CDK2 (0.71) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL14039518 | 0.80 | CDK1 (0.71) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL23641789 | 0.78 | CDK1 (0.45) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL22571127 | 0.78 | CDK2 (0.67) | CDK1CDK2CCNB1CCNE1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | CDK1 2791/4885CDK2 3708/4885CCNB1 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.