Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804436 | 0.81 | ADORA2A (0.66) | ADORA1ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL12379218 | 0.78 | CDK1 (0.71) | CDK1CDK2CCNB1CCNE1ADORA1 | |
| SCHEMBL2152711 | 0.69 | ADORA2A (0.58) | ADORA1ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL27748107 | 0.69 | CDK1 (0.54) | CDK1CDK2CCNB1CCNE1ADORA1 | |
| SCHEMBL5161756 | 0.68 | CDK1 (0.73) | CDK1CDK2CCNB1CCNE1ADORA1 | |
| SCHEMBL11251758 | 0.67 | ADORA2A (0.75) | ADORA1ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL24860314 | 0.67 | ADORA2A (0.75) | ADORA1ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL14131868 | 0.67 | CDK1 (0.64) | CDK1CDK2CCNB1CCNE1ADORA1 | |
| SCHEMBL28083712 | 0.66 | CDK1 (0.76) | CDK1CDK2CCNB1CCNE1ADORA1 | |
| SCHEMBL233129 | 0.66 | ADORA2A (0.64) | CDK1CDK2CCNB1CCNE1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848054-A1 | NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | Daiichi Sankyo Company, Limited (JP) | 2021-07-14 | — | — | EP | disclosed |