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Somatostatin Receptor Ligand

Somatostatin Receptor Ligand

SCHEMBL1237935

CC(O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C(C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](C)N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O.O=C1C=CC(=O)N1.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SSTR1SSTR2SSTR3SSTR4SSTR5

The experimentally established mechanism targets of Somatostatin Receptor Ligand. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SSTR1 known ✓ P30872 12/20 0.65
▸ SSTR2 known ✓ P30874 11/20 0.65
▸ SSTR5 known ✓ P35346 11/20 0.65
▸ SSTR4 known ✓ P31391 10/20 0.65
▸ SSTR3 known ✓ P32745 9/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Somatostatin Receptor Ligand SCHEMBL1164024 0.90 SSTR4 (0.78) SSTR1SSTR2SSTR5SSTR4SSTR3
SCHEMBL29368491 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin Receptor Ligand SCHEMBL8482 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin SCHEMBL29350200 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin Receptor Ligand SCHEMBL3046327 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin Receptor Ligand SCHEMBL31432768 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin Receptor Ligand SCHEMBL12548326 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin Receptor Ligand SCHEMBL16062971 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin SCHEMBL21361053 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3
Somatostatin Receptor Ligand SCHEMBL29386529 0.87 SSTR4 (0.83) SSTR1SSTR2SSTR5SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2464654-A2 THIOL PROTECTING GROUP UCL Business PLC (GB) 2012-06-20 — — EP disclosed
WO-2011018612-A2 THIOL PROTECTING GROUP UCL BUSINESS PLC (GB) 2011-02-17 — — WO disclosed