Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Somatostatin Receptor Ligand. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 known ✓ | P31391 | 13/20 | 0.83 |
| ▸ | SSTR1 known ✓ | P30872 | 11/20 | 0.83 |
| ▸ | SSTR2 known ✓ | P30874 | 10/20 | 0.83 |
| ▸ | SSTR5 known ✓ | P35346 | 10/20 | 0.83 |
| ▸ | SSTR3 known ✓ | P32745 | 10/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Somatostatin Receptor Ligand SCHEMBL16186775 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| SCHEMBL29368491 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin SCHEMBL29350200 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin Receptor Ligand SCHEMBL31432768 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin Receptor Ligand SCHEMBL8482 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin Receptor Ligand SCHEMBL29386529 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin Receptor Ligand SCHEMBL12548326 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin Receptor Ligand SCHEMBL16062971 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin SCHEMBL21361053 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 | |
| Somatostatin Receptor Ligand SCHEMBL3839184 | 1.00 | SSTR4 (0.83) | SSTR4SSTR1SSTR2SSTR5SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323963-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2010-12-23 | — | — | US | claimed |
| US-20100317580-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2010-12-16 | — | — | US | claimed |
| CN-101578287-A | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazoles derivatives, process for their preparation and their use | AETERMA ZENTARIS GMBH (DE) | 2009-11-11 | — | — | CN | claimed |
| EP-2066679-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AEterna Zentaris GmbH (DE) | 2009-06-10 | — | — | EP | claimed |
| US-20080090758-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-04-17 | — | — | US | claimed |
| EP-1900742-A1 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof | AEterna Zentaris GmbH (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2008028934-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-03-13 | — | — | WO | claimed |
| US-12466851-B2 | Manufacture of disulfide bonded peptides | BACHEM HOLDING AG (CH) | 2025-11-11 | — | — | US | disclosed |
| US-20220213139-A1 | MANUFACTURE OF DISULFIDE BONDED PEPTIDES | BACHEM HOLDING AG (CH) | 2022-07-07 | — | — | US | disclosed |
| EP-3956343-A1 | MANUFACTURE OF DISULFIDE BONDED PEPTIDES | Bachem Holding AG (CH) | 2022-02-23 | — | — | EP | disclosed |
| CN-114026107-A | Production of disulfide peptides | 巴克姆股份公司 | 2022-02-08 | — | — | CN | disclosed |
| US-11033642-B2 | Multidentate bifunctional chelating agents for radionuclide complexation in diagnostics and therapy | UNIVERSITAT ZURICH (CH) | 2021-06-15 | — | — | US | disclosed |
| WO-2020212477-A1 | MANUFACTURE OF DISULFIDE BONDED PEPTIDES | BACHEM HOLDING AG (CH) | 2020-10-22 | — | — | WO | disclosed |
| CN-101578287-A | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazoles derivatives, process for their preparation and their use | AETERMA ZENTARIS GMBH (DE) | 2009-11-11 | — | — | CN | disclosed |
| EP-2066679-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AEterna Zentaris GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| US-20080090758-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
| EP-1900742-A1 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof | AEterna Zentaris GmbH (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2008028934-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | AETERNA ZENTARIS GMBH (DE) | 2008-03-13 | — | — | WO | disclosed |
| US-6852688-B2 | Compositions for treating diabetic retinopathy and methods of using same | UNIVERSITY OF FLORIDA (US) | 2005-02-08 | — | — | US | disclosed |
| US-20020045569-A1 | Compositions for treating diabetic retinopathy and methods of using same | FLORIDA, UNIVERSITY OF | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11033642-B2 | Multidentate bifunctional chelating agents for radionuclide complexation in diagnostics and therapy | AOC1, XDH, FOLR1 | SSTR4 875/4885SSTR1 280/4885SSTR2 607/4885 |
| US-20100323963-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | EPCAM, CD99, PTMS | SSTR4 125/4885SSTR1 541/4885SSTR2 833/4885 |
| US-20100317580-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | EPCAM, CD99, PTMS | SSTR4 125/4885SSTR1 541/4885SSTR2 833/4885 |
| US-20080090758-A1 | CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF | EPCAM, CD99, PTMS | SSTR4 125/4885SSTR1 541/4885SSTR2 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.