Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541800 | 0.89 | SCNN1A (0.53) | SCNN1AKCNH2GRM5ALDH1A1KDM4E | |
| SCHEMBL829702 | 0.87 | SCNN1A (0.59) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14190122 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090579 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14190128 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090581 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14088251 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14190132 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14190133 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12433373 | 0.86 | SCNN1A (0.61) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201625-A1 | Organic Comopunds | NOVARTIS AG (CH) | 2011-08-18 | — | — | US | disclosed |
| US-20110201625-A1 | Organic Comopunds | NOVARTIS AG (CH) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201625-A1 | Organic Comopunds | OR10J3, CFTR, CLIC1 | SCNN1A 52/4885KCNH2 49/4885GRM5 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.