Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12380900 | 0.89 | GRIA1 (0.48) | GRIA1GRIA2GRIA4GRIK5CYP1A2 | |
| SCHEMBL12113227 | 0.83 | GRIA1 (0.51) | GRIA1GRIA2GRIA4GRIK5SQOR | |
| SCHEMBL10950422 | 0.72 | MAPK1 (0.43) | MAPK1BLMTYMPTK1HPGD | |
| SCHEMBL12113221 | 0.71 | GRIA1 (0.62) | GRIA1GRIA2GRIA4GRIK5SQOR | |
| SCHEMBL15538150 | 0.71 | HPGD (0.45) | MAPK1BLMTYMPTK1HPGD | |
| SCHEMBL6713750 | 0.71 | MAPK1 (0.42) | MAPK1BLMTYMPTK1HPGD | |
| SCHEMBL12113262 | 0.70 | GRIA1 (0.50) | GRIA1GRIA2GRIA4GRIK5SQOR | |
| SCHEMBL27407778 | 0.70 | MAPK1 (0.41) | MAPK1BLMTYMPTK1HPGD | |
| SCHEMBL29254559 | 0.70 | ALDH1A1 (0.38) | MAPK1BLMTYMPTK1HPGD | |
| SCHEMBL12113265 | 0.69 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989188-B2 | Conjugates for cancer therapy and diagnosis | BIOSIGHT LTD. (IL) | 2011-08-02 | — | — | US | disclosed |