SCHEMBL12384366

SCHEMBL12384366

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)B(O)O

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSK P43235 11/20 0.69
HTRA1 Q92743 2/20 0.66
CTSL P07711 4/20 0.65
CTSS P25774 3/20 0.65
CTSB P07858 2/20 0.65
CAPN1 P07384 2/20 0.62
PSMB5 P28074 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13933719 1.00 CTSK (0.69) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL14539102 1.00 CTSK (0.69) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL13890323 0.99 CTSK (0.70) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL8255445 0.93 HTRA1 (0.67) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL2256230 0.93 HTRA1 (0.67) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL8261580 0.92 CTSK (0.67) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL2253423 0.92 CTSK (0.67) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL14091680 0.91 CTSK (0.69) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL8261559 0.88 CTSK (0.64) CTSKHTRA1CTSLCTSSCTSB
SCHEMBL2251232 0.88 CTSK (0.64) CTSKHTRA1CTSLCTSSCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118183195-B Bidirectional logistics carriage conveying system and energy-saving operation control method thereof 北京物资学院 2026-05-12 CN claimed
EP-4476217-A1 MORPHIC FORMS OF CFT7455 AND METHODS OF MANUFACTURE THEREOF C4 Therapeutics, Inc. (US) 2024-12-18 EP claimed
CN-118660884-A Crystal form of CFT7455 and method for producing same C4医药公司 2024-09-17 CN claimed
US-20240294986-A1 PRECISION MEDICINE FOR SCHIZOPHRENIA AND PSYCHOTIC DISORDERS: OBJECTIVE ASSESSMENT, RISK PREDICTION, PHARMACOGENOMICS, AND REPURPOSED DRUGS THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-09-05 US claimed
EP-4355423-A1 PRECISION MEDICINE FOR SCHIZOPHRENIA AND PSYCHOTIC DISORDERS: OBJECTIVE ASSESSMENT, RISK PREDICTION, PHARMACOGENOMICS, AND REPURPOSED DRUGS Indiana University Research and Technology Corporation (US) 2024-04-24 EP claimed
EP-4313144-A1 COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME Angiex, Inc. (US) 2024-02-07 EP claimed
CN-117355333-A Combination comprising anti-TM 4SF1 antibody and immunotherapeutic agent and method of use thereof 安吉克公司 2024-01-05 CN claimed
US-20230293713-A1 ANTI-TM4SF1 ANTIBODY DRUG CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2023-09-21 US claimed
WO-2023154417-A1 MORPHIC FORMS OF CFT7455 AND METHODS OF MANUFACTURE THEREOF C4 THERAPEUTICS, INC. (US) 2023-08-17 WO claimed
EP-4192450-A1 ADVANTAGEOUS THERAPIES FOR DISORDERS MEDIATED BY IKAROS OR AIOLOS C4 Therapeutics, Inc. (US) 2023-06-14 EP claimed
CN-116194438-A Advantageous treatment of Ikaros or Aiolos mediated disorders C4医药公司 2023-05-30 CN claimed
US-20220403469-A1 Precision Medicine for Schizophrenia and Psychotic Disorders: Objective Assessment, Risk Prediction, Pharmacogenomics, and Repurposed Drugs UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2022-12-22 US claimed
US-20220340908-A1 METHODS FOR DEPLETION OF DELETERIOUS MITOCHONDRIAL GENOMES UNIVERSITY OF MASSACHUSETTS 2022-10-27 US claimed
US-11466252-B2 Expansion and differentiation of inner ear supporting cells and methods of use thereof MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2022-10-11 US claimed
WO-2022204565-A1 COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME ANGIEX, INC. (US) 2022-09-29 WO claimed
EP-4034168-A1 METHODS FOR DEPLETION OF DELETERIOUS MITOCHONDRIAL GENOMES University Of Massachusetts (US) 2022-08-03 EP claimed
WO-2022032132-A1 ADVANTAGEOUS THERAPIES FOR DISORDERS MEDIATED BY IKAROS OR AIOLOS C4 THERAPEUTICS, INC. (US) 2022-02-10 WO claimed
US-20260117185-A1 ENHANCEMENT OF FIBROBLAST PLASTICITY FOR TREATMENT OF DISC DEGENERATION SPINALCYTE, LLC (US) 2026-04-30 US disclosed
US-20070282100-A1 Boronic ester and acid compounds, synthesis and uses MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-06 US disclosed
US-20070282100-A1 Boronic ester and acid compounds, synthesis and uses MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070282100-A1 Boronic ester and acid compounds, synthesis and uses BCL6, BCAP31, CD79B CTSK 2510/4885HTRA1 4673/4885CTSL 3805/4885
US-20260117185-A1 ENHANCEMENT OF FIBROBLAST PLASTICITY FOR TREATMENT OF DISC DEGENERATION HDAC3, HDAC4, GSK3B CTSK 1300/4885HTRA1 678/4885CTSL 712/4885
US-20230293713-A1 ANTI-TM4SF1 ANTIBODY DRUG CONJUGATES AND METHODS OF USING SAME TM9SF4, TM9SF2, TM9SF3 CTSK 1456/4885HTRA1 1618/4885CTSL 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.