SCHEMBL1238451

SCHEMBL1238451

[CH2]C12C=CC(CC1)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776102 0.84
SCHEMBL31096364 0.69
SCHEMBL1781070 0.65
SCHEMBL8068777 0.65
SCHEMBL512359 0.65
SCHEMBL9187316 0.65
SCHEMBL2568694 0.65
SCHEMBL1277405 0.65
SCHEMBL1451452 0.65
SCHEMBL2247304 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105482-A1 Urea Glucokinase Activators NOVO NORDISK A/S (DK) 2009-04-23 US claimed
JP-2009501198-A 2009-01-15 JP claimed
EP-1904467-A1 UREA GLUCOKINASE ACTIVATORS Novo Nordisk A/S (DK) 2008-04-02 EP claimed
WO-2007006814-A1 UREA GLUCOKINASE ACTIVATORS NOVO NORDISK A/S (DK) 2007-01-18 WO claimed
EP-0558104-B1 1,5-Benzodiazepine derivatives and their use in medicine GLAXO WELLCOME SPA (IT) 1998-07-29 EP claimed
US-5637697-A ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ GLAXO SPA (IT) 1997-06-10 US claimed
US-5580895-A GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS GLAXO SPA (IT) 1996-12-03 US claimed
EP-0558104-A1 1,5-Benzodiazepine derivatives and their use in medicine GLAXO S.p.A. (IT) 1993-09-01 EP claimed
WO-1993014074-A1 1,5-BENZODIAZEPINE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO SPA (IT) 1993-07-22 WO claimed
US-4916255-A Method for production of methacrylate ester HITACHI, LTD. (JP) 1990-04-10 US claimed
CN-114401966-A Method for producing cyclic imide compound, composition, compound 富士胶片株式会社 2022-04-26 CN disclosed
CN-113728449-A Composition comprising a metal oxide and a metal oxide 富士胶片株式会社 2021-11-30 CN disclosed
US-9605118-B2 Film and method for manufacturing the same, optical film, polarizer-protecting film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2017-03-28 US disclosed
US-8586614-B2 Urea glucokinase activators NOVO NORDISK A/S (DK) 2013-11-19 US disclosed
EP-2377856-A1 Urea glucokinase activators NOVO NORDISK A/S (DK) 2011-10-19 EP disclosed
EP-0432939-A2 Oil soluble amino-substituted polymers containing graft polymer segments derived form aromatic nitrogen-containing monomers EXXON CHEMICAL PATENTS INC. (US) 1991-06-19 EP disclosed
US-4987200-A METALLIZATION BEFORE POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1991-01-22 US disclosed
EP-0295076-A1 Polyolefins incorporating functional groups, masked functional group-containing monomers, reaction mixtures, and methods for preparing same EXXON CHEMICAL PATENTS INC. (US) 1988-12-14 EP disclosed
US-4552888-A Ascorbic acid ethers in angiogene ELI LILLY AND COMPANY (US) 1985-11-12 US disclosed
EP-0086554-A1 Ascorbic acid ethers and related compounds ELI LILLY AND COMPANY (US) 1983-08-24 EP disclosed