⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18552682 | 0.73 | — | — | |
| SCHEMBL10918418 | 0.66 | CYP1A2 (0.37) | — | |
| SCHEMBL23223073 | 0.59 | — | — | |
| SCHEMBL12490004 | 0.58 | — | — | |
| SCHEMBL1411619 | 0.58 | — | — | |
| SCHEMBL25059955 | 0.58 | MAPT (0.32) | — | |
| SCHEMBL4950753 | 0.58 | — | — | |
| SCHEMBL14490501 | 0.57 | POLB (0.31) | — | |
| SCHEMBL7813275 | 0.57 | ABAT (0.38) | — | |
| SCHEMBL2350926 | 0.56 | SMN1; SMN2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110196141-A1 | LOCKED AND UNLOCKED 2'-O PHOSPHORAMIDITE NUCLEOSIDES, PROCESS OF PREPARATION THEREOF AND OLIGOMERS COMPRISING THE NUCLEOSIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-08-11 | — | — | US | disclosed |