SCHEMBL4950753

SCHEMBL4950753

C=CC1C(=O)C2C=CC1C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11577667 0.75 PRSS1 (0.33)
SCHEMBL18552682 0.69
SCHEMBL895792 0.61
SCHEMBL817418 0.59 PKM (0.30)
SCHEMBL12386263 0.58
SCHEMBL12395331 0.58 CYP1A2 (0.40)
SCHEMBL2979101 0.58
SCHEMBL5709154 0.57
SCHEMBL4955563 0.56 TDP1 (0.32)
SCHEMBL8139841 0.56 ALDH1A1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397813-A Solventless release silicone coating compositions for paper, foil, glass, metal GENERAL ELECTRIC COMPANY (US) 1995-03-14 US claimed
EP-0476426-A1 Preparation of epoxysilicon compounds using rhodium catalysts GENERAL ELECTRIC COMPANY (US) 1992-03-25 EP claimed
US-4421904-A RELEASE COATINGS GENERAL ELECTRIC COMPANY (US) 1983-12-20 US claimed
US-4370358-A PRESSURE SENSITIVE ADHESIVES, EPOXY GROUPS GENERAL ELECTRIC COMPANY (US) 1983-01-25 US claimed
US-7319129-B2 Silsesquioxane derivative and process for producing the same CHISSO CORPORATION (JP) 2008-01-15 US disclosed
EP-1697474-A2 NOVEL SHELF-STABLE PHOTOCURABLE SILICONE COATING FORMULATIONS GENERAL ELECTRIC COMPANY (US) 2006-09-06 EP disclosed
US-7053167-B2 Silsesquioxane derivative having functional group CHISSO CORPORATION (JP) 2006-05-30 US disclosed
US-20060089504-A1 Silsesquioxane derivative having functional group ITO KENYA 2006-04-27 US disclosed
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance CHISSO CORPORATION (JP) 2006-03-09 US disclosed
WO-2005054387-A2 NOVEL SHELF-STABLE PHOTOCURABLE SILICONE COATING FORMULATIONS GENERAL ELECTRIC COMPANY (US) 2005-06-16 WO disclosed
US-20050113479-A1 Novel shelf-stable photocurable silicone coating formulations MOMENTIVE PERFORMANCE MATERIALS INC. 2005-05-26 US disclosed
EP-0844267-B1 Oxa-alkanoic acid-modified epoxy silicone compositions GEN ELECTRIC (US) 2004-09-22 EP disclosed
EP-0476426-A1 Preparation of epoxysilicon compounds using rhodium catalysts GENERAL ELECTRIC COMPANY (US) 1992-03-25 EP disclosed
US-5082686-A Alkylphenol, alkanediol, metalloid salt GENERAL ELECTRIC COMPANY (US) 1992-01-21 US disclosed
US-5010118-A Using polyarylonium salt catalyst GENERAL ELECTRIC COMPANY (US) 1991-04-23 US disclosed
EP-0404031-A1 UV curable non-toxic epoxysilicone release coating compositions and method GENERAL ELECTRIC COMPANY (US) 1990-12-27 EP disclosed
EP-0389927-A2 Epoxysiloxane cure promoters and accelerators for cationic UV cure systems GENERAL ELECTRIC COMPANY (US) 1990-10-03 EP disclosed
US-4421904-A RELEASE COATINGS GENERAL ELECTRIC COMPANY (US) 1983-12-20 US disclosed
US-4370358-A PRESSURE SENSITIVE ADHESIVES, EPOXY GROUPS GENERAL ELECTRIC COMPANY (US) 1983-01-25 US disclosed
US-4279717-A USING BIS-ARYL IODONIUM SALT CATALYST GENERAL ELECTRIC COMPANY (US) 1981-07-21 US disclosed