SCHEMBL1238795

SCHEMBL1238795

Oc1ccccc1N=Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.55
CA12 O43570 2/20 0.55
CA9 Q16790 2/20 0.55
MAPT P10636 7/20 0.55
KDM4E B2RXH2 7/20 0.55
LMNA P02545 6/20 0.55
MEN1 O00255 6/20 0.55
KMT2A Q03164 6/20 0.55
ALDH1A1 P00352 5/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
GAA P10253 4/20 0.55
HTT P42858 4/20 0.55
HPGD P15428 1/20 0.55
TSHR P16473 1/20 0.55
HSD17B10 Q99714 1/20 0.55
L3MBTL1 Q9Y468 3/20 0.51
ATM Q13315 1/20 0.51
POLB P06746 3/20 0.50
NPC1 O15118 2/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2322410 1.00 CA2 (0.55) CA2CA12CA9MAPTKDM4E
SCHEMBL30373259 1.00 CA2 (0.55) CA2CA12CA9MAPTKDM4E
SCHEMBL14337533 1.00 CA2 (0.55) CA2CA12CA9MAPTKDM4E
Lithium Ion SCHEMBL3400785 0.98 CA2 (0.53) CA2CA12CA9MAPTKDM4E
SCHEMBL14982912 0.93 CA12 (0.57) CA2CA12CA9MAPTKDM4E
SCHEMBL3365281 0.88 CA12 (0.49) CA2CA12CA9MAPTKDM4E
SCHEMBL802770 0.88 CA12 (0.49) CA2CA12CA9MAPTKDM4E
SCHEMBL4601929 0.88 CA2 (0.52) CA2CA12CA9MAPTKDM4E
SCHEMBL29690204 0.88 CA2 (0.52) CA2CA12CA9MAPTKDM4E
SCHEMBL4601928 0.88 CA2 (0.52) CA2CA12CA9MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006081327-A2 SMALL MOLECULES THAT REDUCE FUNGAL GROWTH UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2006-08-03 WO claimed
US-4230727-A N-BENZYLIDENEANILINE AND DERIVATIVES WILLIAM H. RORER, INC. (US) 1980-10-28 US claimed
US-4187317-A Sunscreen and erythema treating with N-benzylidene anilenes WILLIAM H. RORER, INC. (US) 1980-02-05 US claimed
US-4176198-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1979-11-27 US claimed
EP-3638647-B1 PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-01-17 EP disclosed
CN-110740987-B Method for mono-N-alkylation of aminophenols SABIC环球技术有限责任公司 2023-04-21 CN disclosed
US-11066354-B2 Process for mono N-alkylation of aminophenol SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-07-20 US disclosed
US-20200140373-A1 PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-05-07 US disclosed
EP-3638647-A1 PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL SABIC Global Technologies B.V. (NL) 2020-04-22 EP disclosed
CN-110740987-A Process for mono-N-alkylation of aminophenols SABIC环球技术有限责任公司 2020-01-31 CN disclosed
WO-2018228981-A1 PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-12-20 WO disclosed
CN-107887616-A A kind of oxidation reduction catalyst of novel transition metal modification and preparation method thereof 中国石油大学(华东) 2018-04-06 CN disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4198349-A ANTIINFLAMMATORY, TOPICAL WILLIAM H. RORER, INC. (US) 1980-04-15 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
US-4187317-A Sunscreen and erythema treating with N-benzylidene anilenes WILLIAM H. RORER, INC. (US) 1980-02-05 US disclosed
US-4176198-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1979-11-27 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066354-B2 Process for mono N-alkylation of aminophenol CYP4A11, CYP4B1, TYR CA2 686/4885CA12 1521/4885CA9 721/4885
US-20200140373-A1 PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL CYP4A11, CYP4B1, TYR CA2 686/4885CA12 1521/4885CA9 721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.