Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157741 | 0.85 | ALDH1A1 (0.42) | KDM4EHPGDTSHRALDH1A1 | |
| SCHEMBL12358186 | 0.84 | CYP1A2 (0.35) | KDM4EHTTATMTSHR | |
| SCHEMBL2158246 | 0.84 | CYP1A2 (0.35) | KDM4EHTTATMTSHR | |
| SCHEMBL6429324 | 0.84 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL6431276 | 0.84 | ACKR3 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2158431 | 0.84 | ALDH1A1 (0.44) | KDM4EHPGDTSHRALDH1A1 | |
| SCHEMBL2158008 | 0.83 | MEN1 (0.52) | MEN1KMT2AHPGD | |
| SCHEMBL2157808 | 0.83 | CYP1A2 (0.39) | TSHRALDH1A1 | |
| SCHEMBL3811287 | 0.82 | MEN1 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3808918 | 0.82 | MEN1 (0.37) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |