Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12396573 | 0.87 | MAOA (0.42) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL2388968 | 0.86 | KDM4E (0.52) | KDM4EATML3MBTL1EDNRBEDNRA | |
| SCHEMBL12259308 | 0.86 | KDM4E (0.52) | KDM4EATML3MBTL1EDNRBEDNRA | |
| SCHEMBL18675904 | 0.82 | MAOA (0.50) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL5021433 | 0.82 | MAOA (0.50) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL11910135 | 0.82 | MAOA (0.53) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL17208658 | 0.82 | MAOA (0.53) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL16356750 | 0.81 | MAOA (0.56) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL5021387 | 0.81 | MAOA (0.56) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL16356751 | 0.81 | MAOA (0.56) | MAOAMAOBACHECYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633316-B2 | Producing method of nitrogen containing condensed heterocyclic compound | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633316-B2 | Producing method of nitrogen containing condensed heterocyclic compound | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110184176-A1 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-07-28 | — | — | US | disclosed |
| US-20110184176-A1 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184176-A1 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND | C5, NISCH, CBR3 | MAOA 185/4885MAOB 176/4885ACHE 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.