SCHEMBL1239664

SCHEMBL1239664

C=Cc1cccc2ncccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
KDM4E B2RXH2 3/20 0.58
CYP3A4 P08684 1/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 3/20 0.46
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 2/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 3/20 0.46
HTT P42858 2/20 0.46
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
BLM P54132 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL9731154 0.91 MAPT (0.48) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL304325 0.86 MAPT (0.56) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL27485338 0.84 MAPT (0.58) MAPTKDM4ECYP3A4MEN1KMT2A
Quinoline SCHEMBL28529356 0.84 ALDH1A1 (0.57) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL30097939 0.81 MAPT (0.37) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL6850607 0.81 MAPT (0.54) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL29956480 0.80 KDM4E (0.58) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL14127415 0.80 MAPT (0.58) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL1071836 0.80 KDM4E (0.58) MAPTKDM4ECYP3A4MEN1KMT2A
SCHEMBL27761309 0.78 KDM4E (0.56) MAPTKDM4ECYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102690229-A Brand new synthesis of Montelukast Sodium and its preparation intermediates SHANGHAI XIANGHUI MEDICAL TECHNOLOGY CO LTD 2012-09-26 CN claimed
US-7892694-B2 Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same KABUSHIKI KAISHA TOSHIBA (JP) 2011-02-22 US claimed
CN-1990525-B Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same TOSHIBA CORP 2010-12-08 CN claimed
US-20070166590-A1 ELECTROLYTIC MEMBRANE, PROCESS FOR PRODUCING THE SAME, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL AND METHOD OF OPERATING THE SAME KABUSHIKI KAISHA TOSHIBA (JP) 2007-07-19 US claimed
CN-1990525-A Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same TOSHIBA KK (JP) 2007-07-04 CN claimed
CN-102690229-A Brand new synthesis of Montelukast Sodium and its preparation intermediates SHANGHAI XIANGHUI MEDICAL TECHNOLOGY CO LTD 2012-09-26 CN disclosed