Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 14/20 | 0.52 |
| ▸ | DDR1 | Q08345 | 13/20 | 0.52 |
| ▸ | ABL1 | P00519 | 11/20 | 0.52 |
| ▸ | BCR | P11274 | 7/20 | 0.52 |
| ▸ | KIT | P10721 | 3/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397301 | 0.97 | DDR2 (0.54) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12397310 | 0.97 | DDR2 (0.48) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12397322 | 0.95 | DDR2 (0.48) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12397318 | 0.90 | ABL1 (0.46) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12397349 | 0.89 | ABL1 (0.44) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12396980 | 0.89 | DDR2 (0.52) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12398490 | 0.87 | CSF1R (0.48) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12398481 | 0.86 | CSF1R (0.50) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12465184 | 0.86 | GPR142 (0.46) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12397273 | 0.86 | ABL1 (0.49) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | DDR2 3140/4885DDR1 1572/4885ABL1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.