SCHEMBL12402811

SCHEMBL12402811

CCOCCCOCC(O)CN1CCN(C)CC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 4/20 0.52
USP2 O75604 2/20 0.52
ALOX15 P16050 1/20 0.52
GLA P06280 1/20 0.51
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
LMNA P02545 3/20 0.44
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
RAB9A P51151 2/20 0.41
MAPK1 P28482 2/20 0.39
HTT P42858 2/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10005231 0.89 KDM4E (0.64) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL18551060 0.89 KDM4E (0.58) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL18551052 0.89 KDM4E (0.58) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL26376109 0.89 KDM4E (0.58) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL21477058 0.87 KDM4E (0.57) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL21477194 0.87 KDM4E (0.57) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL11154511 0.86 KDM4E (0.58) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL12170225 0.84 KDM4E (0.51) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL13924017 0.84 KDM4E (0.55) ALDH1A1KDM4EUSP2ALOX15GLA
SCHEMBL12153675 0.83 KDM4E (0.46) ALDH1A1KDM4EUSP2ALOX15GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 ALDH1A1 2720/4885KDM4E 3988/4885USP2 2983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.