Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154511 | 0.94 | KDM4E (0.58) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL23673724 | 0.93 | USP2 (0.71) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL8394063 | 0.93 | USP2 (0.71) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL21477058 | 0.92 | KDM4E (0.57) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL21477194 | 0.92 | KDM4E (0.57) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL13924017 | 0.91 | KDM4E (0.55) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL12402811 | 0.89 | ALDH1A1 (0.52) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL12170225 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301621 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1USP2ALOX15GLA | |
| SCHEMBL301640 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1USP2ALOX15GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120006229-A1 | AQUEOUS SOLUTION OF PIPERAZINYL-CONTAINING SILANOL COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-7897716-B2 | Polyorganosiloxane compositions for the treatment of substrates | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2011-03-01 | — | — | US | disclosed |
| US-7585494-B2 | Formulations used for the treatment of substrate surfaces | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2009-09-08 | — | — | US | disclosed |