SCHEMBL12402829

SCHEMBL12402829

OC(COCC(O)COCC(COCC1CO1)(COCC1CO1)COCC1CO1)COCC(COCC1CO1)(COCC1CO1)COCC1CO1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12270861 0.91 TSHR (0.41) TSHRMAPK1ALDH1A1SMN1; SMN2
SCHEMBL12158330 0.88 TSHR (0.49) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL12158343 0.88 TSHR (0.42) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL27051341 0.85 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL13384368 0.84 ALDH1A1 (0.43) TSHRMAPK1ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL14156747 0.84 TSHR (0.72) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL216984 0.82 TSHR (0.50) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL36499 0.82 TSHR (0.67) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL12158328 0.82 TSHR (0.46) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL16314638 0.82 TSHR (0.46) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9585387-B1 PEHAM dendrimers for use in agriculture STARPHARMA PTY LTD (AU) 2017-03-07 US disclosed
US-9585387-B1 PEHAM dendrimers for use in agriculture STARPHARMA PTY LTD (AU) 2017-03-07 US disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US disclosed
US-7981444-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-07-19 US disclosed
US-7981444-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-07-19 US disclosed
WO-2009110971-A2 PROCESS FOR CONVERTING MULTIFUNCTIONAL ALIPHATIC ALCOHOLS DENDRITIC NANOTECHNOLOGIES, INC. (US) 2009-09-11 WO disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 US disclosed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 TSHR 3651/4885MAPK1 4174/4885ALDH1A1 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.