⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981116 | 0.72 | — | — | |
| SCHEMBL1558716 | 0.72 | — | — | |
| SCHEMBL3197752 | 0.69 | — | — | |
| SCHEMBL6003789 | 0.68 | — | — | |
| SCHEMBL14889545 | 0.68 | — | — | |
| SCHEMBL8508168 | 0.68 | — | — | |
| SCHEMBL4582932 | 0.68 | — | — | |
| SCHEMBL7822211 | 0.67 | — | — | |
| SCHEMBL13492169 | 0.66 | PTGS1 (0.58) | — | |
| SCHEMBL13340881 | 0.65 | NUAK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344467-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-12-03 | — | — | US | disclosed |
| CN-102906079-B | Germination-stimulating carbamate derivatives and process for their preparation | NAT UNIV CORP UNIV KOBE | 2014-11-05 | — | — | CN | disclosed |
| US-20140038965-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8481534-B2 | 5- and 6-membered heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-20110183976-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | FMR LLC | 2011-07-28 | — | — | US | disclosed |
| US-7666904-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH LLC (US) | 2010-02-23 | — | — | US | disclosed |
| US-7495027-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH (US) | 2009-02-24 | — | — | US | disclosed |
| US-20090036439-A1 | 3-ARYL-4-HYDROXYFURANONE COMPOUNDS AND THE HUMAN AND ANIMAL HEALTH USE THEREOF | WYETH (US) | 2009-02-05 | — | — | US | disclosed |