⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945135 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL9197663 | 0.70 | PTGS1 (0.47) | — | |
| SCHEMBL16446607 | 0.70 | — | — | |
| SCHEMBL12404372 | 0.69 | — | — | |
| SCHEMBL1558716 | 0.67 | — | — | |
| SCHEMBL9192106 | 0.66 | KMT2A (0.58) | — | |
| SCHEMBL9192631 | 0.62 | PTGS1 (0.47) | — | |
| SCHEMBL427425 | 0.62 | — | — | |
| SCHEMBL15127518 | 0.60 | — | — | |
| SCHEMBL31496832 | 0.59 | CYP3A4 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102084004-A | Hybridization compositions and methods | DAKO DENMARK AS | 2011-06-01 | — | — | CN | claimed |
| CN-102046808-A | Compositions and methods for detecting chromosomal aberrations using novel hybridization buffers | DAKO DENMARK AS | 2011-05-04 | — | — | CN | claimed |
| CN-102046808-B | Compositions and methods for detecting chromosomal aberrations using novel hybridization buffers | 丹麦达科有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-102084004-B | Cross combination thing and method | DAKO DENMARK A/S (DK) | 2016-01-20 | — | — | CN | disclosed |
| CN-102084004-A | Hybridization compositions and methods | DAKO DENMARK AS | 2011-06-01 | — | — | CN | disclosed |
| CN-102046808-A | Compositions and methods for detecting chromosomal aberrations using novel hybridization buffers | DAKO DENMARK AS | 2011-05-04 | — | — | CN | disclosed |
| US-7666904-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH LLC (US) | 2010-02-23 | — | — | US | disclosed |
| US-7666904-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH LLC (US) | 2010-02-23 | — | — | US | disclosed |
| US-7666904-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH LLC (US) | 2010-02-23 | — | — | US | disclosed |
| US-7495027-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495027-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495027-B2 | 3-aryl-4-hydroxyfuranone compounds and the human and animal health use thereof | WYETH (US) | 2009-02-24 | — | — | US | disclosed |
| US-20090036439-A1 | 3-ARYL-4-HYDROXYFURANONE COMPOUNDS AND THE HUMAN AND ANIMAL HEALTH USE THEREOF | WYETH (US) | 2009-02-05 | — | — | US | disclosed |
| US-20090036439-A1 | 3-ARYL-4-HYDROXYFURANONE COMPOUNDS AND THE HUMAN AND ANIMAL HEALTH USE THEREOF | WYETH (US) | 2009-02-05 | — | — | US | disclosed |
| US-20090036439-A1 | 3-ARYL-4-HYDROXYFURANONE COMPOUNDS AND THE HUMAN AND ANIMAL HEALTH USE THEREOF | WYETH (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1654244-A1 | 3-ARYL-4-HYDROXYFURANONE COMPOUNDS AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS CONTAINING THEM | Wyeth (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20050054721-A1 | 3-Aryl-4-Hydroxyfuranone compounds and the human and animal health use thereof | WYETH (US) | 2005-03-10 | — | — | US | disclosed |
| WO-2005019196-A1 | 3-ARYL-4-HYDROXYFURANONE COMPOUNDS AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS CONTAINING THEM | WYETH (US) | 2005-03-03 | — | — | WO | disclosed |