Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | SSTR4 | P31391 | 7/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621159 | 0.93 | SIGMAR1 (0.58) | SIGMAR1SSTR4GLSHPGDRECQL | |
| SCHEMBL29765379 | 0.92 | SIGMAR1 (0.70) | SIGMAR1SSTR4DRD4 | |
| SCHEMBL14391516 | 0.84 | HPGD (0.50) | SSTR4HPGDRECQL | |
| SCHEMBL357853 | 0.84 | HPGD (0.50) | SSTR4HPGDRECQL | |
| SCHEMBL1912176 | 0.79 | HPGD (0.44) | SIGMAR1SSTR4SSTR1HPGDRECQL | |
| SCHEMBL356606 | 0.79 | GRM5 (0.60) | SSTR4SSTR1USP30 | |
| SCHEMBL31654067 | 0.79 | GRM5 (0.60) | SSTR4SSTR1USP30 | |
| SCHEMBL13929210 | 0.79 | SIGMAR1 (0.69) | SIGMAR1DRD4 | |
| SCHEMBL25096572 | 0.79 | HRH3 (0.47) | SIGMAR1HPGDRECQL | |
| SCHEMBL25103815 | 0.79 | HRH3 (0.47) | SIGMAR1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166135-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-07-07 | — | — | US | disclosed |
| US-20110166135-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166135-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | PDE10A, PDE3A, PDE3B | SIGMAR1 1436/4885SSTR4 1900/4885SSTR1 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.