Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 14/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 5/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 13/20 | 0.81 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891144 | 0.92 | DPP4 (0.84) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL8261870 | 0.92 | DPP4 (0.84) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL1243362 | 0.83 | DPP4 (0.71) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL5114076 | 0.83 | DPP4 (0.71) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL8261904 | 0.82 | DPP4 (0.88) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL12891244 | 0.78 | DPP4 (0.86) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL8263878 | 0.78 | DPP4 (0.86) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| Trifluoroacetic Acid SCHEMBL1242611 | 0.78 | DPP4 (0.81) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| Trifluoroacetic Acid SCHEMBL1243191 | 0.78 | DPP4 (0.73) | DPP4DPP7CYP2D6KCNH2DPP9 | |
| SCHEMBL12891239 | 0.77 | DPP4 (0.67) | DPP4DPP7CYP2D6KCNH2DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884104-B2 | Such as (3R,4R)-1-Pyrimidin-4-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine bis-trifluoroacetic acid salt | MERCK SHARP & DOHME CORP. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20080076773-A1 | Aminopiperidines as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes | MERCK SHARP & DOHME LLC | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076773-A1 | Aminopiperidines as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes | DPP4, DPP3, DPP7 | DPP4 1/4885DPP7 3/4885CYP2D6 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.